Johns Hopkins ABX Guide
Hepatitis E
MICROBIOLOGY
- An RNA virus is transmitted via enteric routes in epidemics and sporadic cases, similar to HAV.
- Modes of transmission include waterborne, zoonotic/foodborne and, less commonly, through blood transfusion and perinatally.
- Eight genotypes described, with four causing human illness and distinct transmission means suspected.
- Genotypes 1, 2: predominantly fecal-contaminated water in developing countries worldwide.
- Genotypes 3, 4: Zoonotic transmission appears more foodborne (insufficiently cooked game meat or pork products and shellfish in North America, Western Europe, and Japan).
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Last updated: January 13, 2023
Citation
Auwaerter, Paul G, and Juhi Moon. "Hepatitis E." Johns Hopkins ABX Guide, The Johns Hopkins University, 2023. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540267/all/Hepatitis_E.
Auwaerter PG, Moon J. Hepatitis E. Johns Hopkins ABX Guide. The Johns Hopkins University; 2023. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540267/all/Hepatitis_E. Accessed April 24, 2025.
Auwaerter, P. G., & Moon, J. (2023). Hepatitis E. In Johns Hopkins ABX Guide. The Johns Hopkins University. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540267/all/Hepatitis_E
Auwaerter PG, Moon J. Hepatitis E [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2023. [cited 2025 April 24]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540267/all/Hepatitis_E.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC
T1 - Hepatitis E
ID - 540267
A1 - Auwaerter,Paul,M.D.
AU - Moon,Juhi,M.D.
Y1 - 2023/01/13/
BT - Johns Hopkins ABX Guide
UR - https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540267/all/Hepatitis_E
PB - The Johns Hopkins University
DB - Pediatrics Central
DP - Unbound Medicine
ER -
