Hepatitis B (HBV) vaccines

Kathryn Dzintars, Pharm.D., BCPS, Fidelia Bernice, Pharm.D., BCIDP
Pediatric Dosing Author: Bethany Sharpless Chalk, Pharm.D., BCPPS

VACCINE TYPE

  • Hepilsav-B: yeast-derived vaccine created with a novel adjuvant Toll-like receptor 9 (TLR9) agonist.
  • Recombivax HB: recombinant vaccine produced by Saccharomyces cerevisiae (baker’s yeast).
  • Engerix-B: recombinant vaccine, also produced by Saccharomyces cerevisiae.
  • Twinrix: bivalent vaccine protecting both hepatitis A and B: HAV (720 ELISA units/mL) and HBV (20 mcg HBsAg/mL).

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Last updated: May 10, 2025