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    Hantavirus

    Paul G. Auwaerter, M.D.
    Hantavirus is a topic covered in the Johns Hopkins ABX Guide.

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    MICROBIOLOGY

    • Segmented, negative sense RNA virus. Large number of species (23 to date) with more discovered regularly.
    • Member of Bunyaviridae. Unlike other viruses in this family that are arthropod borne, hantaviruses are rodent borne viruses associated with specific reservoirs.
    • In the U.S., geographic locales differ:
      • Southeast: deer mice, cotton and rice rats
      • Northeast: white-footed mouse has been associated
    • Transmission to humans through inhalation of aerosolized saliva, urine or feces of reservoir host.
    • Hantavirus New World: (e.g., Sin Nombre virus) known to cause hantavirus pulmonary syndrome (HPS)
      • Carried by the New World rats and mice, family Muridae, subfamily Sigmodontinae; these rodents are not found in urban sites.
        • Deer mouse
        • Cotton rat
        • Rice rat
        • White-footed mouse
    • Hantaan virus, Old World: may cause hemorrhagic fever with renal syndrome (HFRS).
      • Puumala virus, a hantavirus carried in bank voles, may cause Nephropathia epidemica in humans primarily in Europe.
      • Dobrava-Belgrade virus (DOBV) causes a more severe HFRS, again in Europe.
      • Hantaan virus: HFRS in Asia
      • Seoul virus: HFRS in Asia.

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    Last updated: November 6, 2015

    Citation

    Auwaerter, Paul G. "Hantavirus." Johns Hopkins ABX Guide, The Johns Hopkins University, 2015. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540255/all/Hantavirus.
    Auwaerter PG. Hantavirus. Johns Hopkins ABX Guide. The Johns Hopkins University; 2015. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540255/all/Hantavirus. Accessed April 21, 2019.
    Auwaerter, P. G. (2015). Hantavirus. In Johns Hopkins ABX Guide. Available from https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540255/all/Hantavirus
    Auwaerter PG. Hantavirus [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2015. [cited 2019 April 21]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540255/all/Hantavirus.
    * Article titles in AMA citation format should be in sentence-case
    TY - ELEC T1 - Hantavirus ID - 540255 A1 - Auwaerter,Paul,M.D. Y1 - 2015/11/06/ BT - Johns Hopkins ABX Guide UR - https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540255/all/Hantavirus PB - The Johns Hopkins University DB - Pediatrics Central DP - Unbound Medicine ER -