Helicobacter pylori

PATHOGENS

  • Helicobacter pylori: attaches to gastric cells inducing inflammation and cytokine production.
  • Culture: if performed, typically is done following treatment failure.
    • Requires endoscopy with gastric biopsy, most frequently from the antrum.
      • The optimal specimen is to place in culture within three hours of collection.
      • Specimen transport can be done in Brucella broth with 20% glycerol.
      • The most frequently employed culture media is Brucella or Columbia agar with 7-10% blood to improve growth in a 5-10% oxygen environment.
      • Cultures are held for up to 10 days due to slow growth.
  • Antimicrobial characteristics:

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Last updated: April 16, 2023