Johns Hopkins ABX Guide
Gentamicin
Gentamicin is a topic covered in the Johns Hopkins ABX Guide.
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INDICATIONS
FDA
FDA
- Serious infections caused by susceptible strains of organism.
- With the exception of uncomplicated UTI, aminoglycosides are generally used in combination for serious infections.
- Bacterial septicemia, including neonatal sepsis
- Skin, bone and soft tissue infections (including burns)
- Meningitis (poor penetration)
- Urinary tract
- Respiratory tract (poor penetration)
- Gastrointestinal tract (including peritonitis)
- Inflammatory ocular conditions that are steroid-responsive (opthalmic ointment and suspension)
NON-FDA APPROVED USES
NON-FDA APPROVED USES
- Pneumonia, hospital-acquired (in combination with a beta-lactam, beta-lactam/beta-lactamase inhibitor, or a third/fourth-generation cephalosporin)
- Intra-abdominal infection (in combination with an agent with Gram-positive and anaerobe coverage)
- Enterococcal endocarditis (in combination with ampicillin)
- Pelvic inflammatory disease (PID, in combination with clindamycin)
- Infections caused by P. aeruginosa (in combination with a beta-lactam, beta-lactam/beta-lactamase inhibitor, or a third/fourth-generation cephalosporin)
- Brucella Species
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INDICATIONS
FDA
FDA
- Serious infections caused by susceptible strains of organism.
- With the exception of uncomplicated UTI, aminoglycosides are generally used in combination for serious infections.
- Bacterial septicemia, including neonatal sepsis
- Skin, bone and soft tissue infections (including burns)
- Meningitis (poor penetration)
- Urinary tract
- Respiratory tract (poor penetration)
- Gastrointestinal tract (including peritonitis)
- Inflammatory ocular conditions that are steroid-responsive (opthalmic ointment and suspension)
NON-FDA APPROVED USES
NON-FDA APPROVED USES
- Pneumonia, hospital-acquired (in combination with a beta-lactam, beta-lactam/beta-lactamase inhibitor, or a third/fourth-generation cephalosporin)
- Intra-abdominal infection (in combination with an agent with Gram-positive and anaerobe coverage)
- Enterococcal endocarditis (in combination with ampicillin)
- Pelvic inflammatory disease (PID, in combination with clindamycin)
- Infections caused by P. aeruginosa (in combination with a beta-lactam, beta-lactam/beta-lactamase inhibitor, or a third/fourth-generation cephalosporin)
- Brucella Species
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Last updated: April 5, 2017
Citation
Dzintars, Kathryn, and Paul A Pham. "Gentamicin." Johns Hopkins ABX Guide, The Johns Hopkins University, 2017. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540245/all/Gentamicin.
Dzintars K, Pham PA. Gentamicin. Johns Hopkins ABX Guide. The Johns Hopkins University; 2017. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540245/all/Gentamicin. Accessed January 20, 2020.
Dzintars, K., & Pham, P. A. (2017). Gentamicin. In Johns Hopkins ABX Guide. Available from https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540245/all/Gentamicin
Dzintars K, Pham PA. Gentamicin [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2017. [cited 2020 January 20]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540245/all/Gentamicin.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC
T1 - Gentamicin
ID - 540245
A1 - Dzintars,Kathryn,Pharm.D., BCPS
AU - Pham,Paul,Pharm.D.
Y1 - 2017/04/05/
BT - Johns Hopkins ABX Guide
UR - https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540245/all/Gentamicin
PB - The Johns Hopkins University
DB - Pediatrics Central
DP - Unbound Medicine
ER -