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Fever and Neutropenia

Fever and Neutropenia is a topic covered in the Johns Hopkins ABX Guide.

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  • Febrile neutropenia[7]
    • Fever: single oral temp ≥ 38.3°C (101°F) or temp ≥ 38°C (100.4°F) sustained for 1h AND
    • Neutropenia: absolute neutrophil count (ANC) < 500 cells/mm3 OR ANC predicted to decrease to < 500 cells/mm3 in 48h
  • Caveat: Signs and symptoms typical of bacterial infection (i.e., induration, erythema, pustulation, CXR infiltrates, CSF pleocytosis) may be absent, and course may be fulminant.

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Last updated: April 2, 2017


Spacek, Lisa A. "Fever and Neutropenia." Johns Hopkins ABX Guide, The Johns Hopkins University, 2017. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540221/1.0/Fever_and_Neutropenia.
Spacek LA. Fever and Neutropenia. Johns Hopkins ABX Guide. The Johns Hopkins University; 2017. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540221/1.0/Fever_and_Neutropenia. Accessed June 24, 2019.
Spacek, L. A. (2017). Fever and Neutropenia. In Johns Hopkins ABX Guide. Available from https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540221/1.0/Fever_and_Neutropenia
Spacek LA. Fever and Neutropenia [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2017. [cited 2019 June 24]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540221/1.0/Fever_and_Neutropenia.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Fever and Neutropenia ID - 540221 A1 - Spacek,Lisa,M.D., Ph.D. Y1 - 2017/04/02/ BT - Johns Hopkins ABX Guide UR - https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540221/1.0/Fever_and_Neutropenia PB - The Johns Hopkins University DB - Pediatrics Central DP - Unbound Medicine ER -