Cytomegalovirus is a topic covered in the Johns Hopkins ABX Guide.

To view the entire topic, please or purchase a subscription.

Pediatrics Central™ is an all-in-one application that puts valuable medical information, via your mobile device or the web, in the hands of clinicians treating infants, children, and adolescents. Explore these free sample topics:

Pediatrics Central

-- The first section of this topic is shown below --

MICROBIOLOGY

  • Ubiquitous, large, enveloped dsDNA betaherpesvirus; establishes lifelong latency after primary infection.
  • Transmitted sexually or by close contact, blood or tissue exposure, perinatally. Cultured from urine, blood, throat, tears, stool, cervix, semen, breast milk.
  • Seroprevalence increases with age. Adult seroprevalence rates range from 40-100% and are highest in developing countries.
  • Exhibits slow growth in cultured cells (can be up to 6 weeks until cytopathic effect is detected in tissue culture) and cytopathology is characterized by large cells with nuclear (Cowdry owl’s eye) and cytoplasmic inclusions.
  • Isolation of virus or detection of viral proteins or nucleic acid defines CMV infection. Presence of signs/symptoms of end organ disease + CMV infection = CMV disease.

-- To view the remaining sections of this topic, please or purchase a subscription --

Last updated: June 25, 2012

Citation

* When formatting your citation, note that all book, journal, and database titles should be italicized* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Cytomegalovirus ID - 540153 A1 - Spacek,Lisa,M.D., Ph.D. Y1 - 2012/06/25/ BT - Johns Hopkins ABX Guide UR - https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540153/all/Cytomegalovirus PB - The Johns Hopkins University DB - Pediatrics Central DP - Unbound Medicine ER -