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    Cryptococcal Meningitis

    John G. Bartlett, M.D.
    Cryptococcal Meningitis is a topic covered in the Johns Hopkins ABX Guide.

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    PATHOGENS

    • Main human pathogen:
      • Cryptococcus neoformans (predominant)
        • Four serotypes (A to D) described based upon the capsule components.
        • Three varieties described as causing human disease C. neoformans v. neoformans (most common), v. gattii, and v. grubii (recently established).
      • C. gattii: unlike C. neoformans, is more commonly seen in healthy hosts.
        • Has reduced sensitivity to fluconazole and appears to be more virulent.

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    Last updated: February 3, 2016

    Citation

    Bartlett, John G. "Cryptococcal Meningitis." Johns Hopkins ABX Guide, The Johns Hopkins University, 2016. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540146/all/Cryptococcal_Meningitis.
    Bartlett JG. Cryptococcal Meningitis. Johns Hopkins ABX Guide. The Johns Hopkins University; 2016. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540146/all/Cryptococcal_Meningitis. Accessed April 19, 2019.
    Bartlett, J. G. (2016). Cryptococcal Meningitis. In Johns Hopkins ABX Guide. Available from https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540146/all/Cryptococcal_Meningitis
    Bartlett JG. Cryptococcal Meningitis [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2016. [cited 2019 April 19]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540146/all/Cryptococcal_Meningitis.
    * Article titles in AMA citation format should be in sentence-case
    TY - ELEC T1 - Cryptococcal Meningitis ID - 540146 A1 - Bartlett,John,M.D. Y1 - 2016/02/03/ BT - Johns Hopkins ABX Guide UR - https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540146/all/Cryptococcal_Meningitis PB - The Johns Hopkins University DB - Pediatrics Central DP - Unbound Medicine ER -