Clostridium tetani (Tetanus)

Clostridium tetani (Tetanus) is a topic covered in the Johns Hopkins ABX Guide.

To view the entire topic, please or .

Pediatrics Central™ is an all-in-one application that puts valuable medical information, via your mobile device or the web, in the hands of clinicians treating infants, children, and adolescents. Explore these free sample topics:

-- The first section of this topic is shown below --

MICROBIOLOGY

  • Clostridium tetani is a Gram-positive bacillus, obligate anaerobe.
    • If culture enters the endospore stage, it may have classic tennis racquet morphology [Fig 1].
  • Spores are widespread in soil and animal feces.
  • The rod-shaped appearance on a Gram stain is often likened to drumsticks or tennis rackets.
  • Toxin, tetanospasmin, causes tetanus: unopposed muscle spasm and contraction due to interference of toxin with neurotransmitters (including GABA and glycine).

-- To view the remaining sections of this topic, please or --

MICROBIOLOGY

  • Clostridium tetani is a Gram-positive bacillus, obligate anaerobe.
    • If culture enters the endospore stage, it may have classic tennis racquet morphology [Fig 1].
  • Spores are widespread in soil and animal feces.
  • The rod-shaped appearance on a Gram stain is often likened to drumsticks or tennis rackets.
  • Toxin, tetanospasmin, causes tetanus: unopposed muscle spasm and contraction due to interference of toxin with neurotransmitters (including GABA and glycine).

There's more to see -- the rest of this topic is available only to subscribers.

Last updated: January 12, 2023