Johns Hopkins ABX Guide
Cholangitis
PATHOGENS
- Frequently polymicrobial, usually gastrointestinal flora.
- E. coli (22-50%), Klebsiella species (15-20%), Enterobacter species (5-10%)
- Enterococcus (10-20%) and anaerobes (often of unclear relevance)
- The pathogenic role of enterococci and anaerobes is not well defined, and empirical coverage for these organisms is not usually required.
- Resistant pathogens may be encountered in patients with healthcare-associated infections or recent antibiotic use; empirical coverage should be adjusted accordingly.
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Last updated: October 18, 2022
Citation
, Carmen DeMarco, and Christopher F Carpenter. "Cholangitis." Johns Hopkins ABX Guide, The Johns Hopkins University, 2022. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540121/all/Cholangitis.
C, Carpenter CF. Cholangitis. Johns Hopkins ABX Guide. The Johns Hopkins University; 2022. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540121/all/Cholangitis. Accessed July 31, 2025.
, C., & Carpenter, C. F. (2022). Cholangitis. In Johns Hopkins ABX Guide. The Johns Hopkins University. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540121/all/Cholangitis
C, Carpenter CF. Cholangitis [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2022. [cited 2025 July 31]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540121/all/Cholangitis.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC
T1 - Cholangitis
ID - 540121
A1 - ,Carmen DeMarco,M.D.
AU - Carpenter,Christopher,M.D.
Y1 - 2022/10/18/
BT - Johns Hopkins ABX Guide
UR - https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540121/all/Cholangitis
PB - The Johns Hopkins University
DB - Pediatrics Central
DP - Unbound Medicine
ER -
