Chlamydia pneumoniae
Chlamydia pneumoniae is a topic covered in the Johns Hopkins ABX Guide.
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MICROBIOLOGY
- C. pneumoniae is an obligate intracellular Gram-negative bacterium.
- It grows like a virus (requires cell culture systems) but is a bacterium with RNA and DNA.
- An intracellular organism parasite requires a host cell for ATP/GTP.
- Known to also cause disease in koalas, reptiles and amphibians.
- The elementary body is metabolically inactive and has a rigid cell wall that permits survival outside the cell and is infectious [Fig]. Inside the cell, it is seen as a reticulate body that is metabolically active but non-infectious.
- Incubation culture to positivity: average 21 d.
- Historically known as the "TWAR" agent, two of the original isolates were from Taiwan.
- Formerly called Chalmydophila pneumoniae.
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MICROBIOLOGY
- C. pneumoniae is an obligate intracellular Gram-negative bacterium.
- It grows like a virus (requires cell culture systems) but is a bacterium with RNA and DNA.
- An intracellular organism parasite requires a host cell for ATP/GTP.
- Known to also cause disease in koalas, reptiles and amphibians.
- The elementary body is metabolically inactive and has a rigid cell wall that permits survival outside the cell and is infectious [Fig]. Inside the cell, it is seen as a reticulate body that is metabolically active but non-infectious.
- Incubation culture to positivity: average 21 d.
- Historically known as the "TWAR" agent, two of the original isolates were from Taiwan.
- Formerly called Chalmydophila pneumoniae.
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Last updated: February 8, 2023
Citation
Fabre, Valeria. "Chlamydia Pneumoniae." Johns Hopkins ABX Guide, The Johns Hopkins University, 2023. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540117/all/Chlamydia_pneumoniae.
Fabre V. Chlamydia pneumoniae. Johns Hopkins ABX Guide. The Johns Hopkins University; 2023. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540117/all/Chlamydia_pneumoniae. Accessed March 29, 2023.
Fabre, V. (2023). Chlamydia pneumoniae. In Johns Hopkins ABX Guide. The Johns Hopkins University. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540117/all/Chlamydia_pneumoniae
Fabre V. Chlamydia Pneumoniae [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2023. [cited 2023 March 29]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540117/all/Chlamydia_pneumoniae.
* Article titles in AMA citation format should be in sentence-case
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A1 - Fabre,Valeria,M.D.
Y1 - 2023/02/08/
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PB - The Johns Hopkins University
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