Johns Hopkins ABX Guide
Cefuroxime
INDICATIONS
FDA
FDA
- Uncomplicated urinary tract infections caused by E. coli or K. pneumoniae (PO and IV)
- Uncomplicated skin and skin-structure infections caused by S. aureus or S. pyogenes (PO and IV) E. coli, Klebsiella spp., and Enterobacter spp. (IV)
- Impetigo (pediatric patients) (PO)
- Upper respiratory tract infections including acute otitis media, acute maxillary sinusitis, acute exacerbation of chronic bronchitis, and pharyngitis/tonsillitis (PO)
- Early Lyme disease (erythema migrans) caused by B. burgdorferi (PO)
- Lower respiratory tract infections including community-acquired pneumonia (CAP, IV)
- Septicemia caused by S. aureus, S. pneumoniae, E. coli, H. influenzae, Klebsiella spp. (IV only)
- Meningitis S. pneumoniae, H. influenzae, N. meningitidis, and S. aureus (MSSA) (IV only).
- Author’s comment: Nafcillin preferred for MSSA meningitis.
- Bone and joint infections caused by MSSA (IV)
- Uncomplicated urethral and endocervical gonorrhea and ano-rectal gonorrhea (females) caused by N. gonorrhoeae (no longer recommended, oral and IV)
NON-FDA APPROVED USES
NON-FDA APPROVED USES
- Late Lyme arthritis
- CAP (oral cefuroxime)
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Last updated: March 16, 2025
Citation
, Caitlin Soto, PharmD, BCIDP, and Edina Avdic. "Cefuroxime." Johns Hopkins ABX Guide, The Johns Hopkins University, 2025. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540105/12/Cefuroxime.
C, Avdic E. Cefuroxime. Johns Hopkins ABX Guide. The Johns Hopkins University; 2025. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540105/12/Cefuroxime. Accessed July 20, 2025.
, C., & Avdic, E. (2025). Cefuroxime. In Johns Hopkins ABX Guide. The Johns Hopkins University. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540105/12/Cefuroxime
C, Avdic E. Cefuroxime [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2025. [cited 2025 July 20]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540105/12/Cefuroxime.
* Article titles in AMA citation format should be in sentence-case
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T1 - Cefuroxime
ID - 540105
A1 - ,Caitlin Soto, PharmD, BCIDP,
AU - Avdic,Edina,Pharm.D.
Y1 - 2025/03/16/
BT - Johns Hopkins ABX Guide
UR - https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540105/12/Cefuroxime
PB - The Johns Hopkins University
DB - Pediatrics Central
DP - Unbound Medicine
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