Johns Hopkins ABX Guide
Capnocytophaga spp.
Capnocytophaga spp. is a topic covered in the Johns Hopkins ABX Guide.
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MICROBIOLOGY
- C. canimorsus (previously known as DF-2, dysgonic fermenter) and C. cynodegmi (previously known as DF-2 like organism) are facultatively anaerobic Gram-negative rods, part of normal oral flora of dogs and cats.
- C. cynodegmi is considered less virulent than C. canimorsus.
- Other Capnocytophaga species may be part of animal oral flora, or normal human oral flora/dental plaques, e.g., C. sputigena, C. canis, C. endodontalis sp. nov. and C. gingivalis.
- Organisms have a long, fusiform appearance on gram stain, making it distinctive enough to consider morphologic identification pending cx results.
- Organisms considered fastidious by the micro lab.
- Most strains are resistant to polymyxin, fusidic acid, fosfomycin and trimethoprim.
- Variably active: beta-lactams, erythromycin, quinolones, metronidazole, vancomycin, aminoglycosides.
- Usually active: beta-lactam/beta-lactamase inhibitors and carbapenems.
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MICROBIOLOGY
- C. canimorsus (previously known as DF-2, dysgonic fermenter) and C. cynodegmi (previously known as DF-2 like organism) are facultatively anaerobic Gram-negative rods, part of normal oral flora of dogs and cats.
- C. cynodegmi is considered less virulent than C. canimorsus.
- Other Capnocytophaga species may be part of animal oral flora, or normal human oral flora/dental plaques, e.g., C. sputigena, C. canis, C. endodontalis sp. nov. and C. gingivalis.
- Organisms have a long, fusiform appearance on gram stain, making it distinctive enough to consider morphologic identification pending cx results.
- Organisms considered fastidious by the micro lab.
- Most strains are resistant to polymyxin, fusidic acid, fosfomycin and trimethoprim.
- Variably active: beta-lactams, erythromycin, quinolones, metronidazole, vancomycin, aminoglycosides.
- Usually active: beta-lactam/beta-lactamase inhibitors and carbapenems.
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Last updated: May 5, 2019
Citation
Auwaerter, Paul. "Capnocytophaga Spp." Johns Hopkins ABX Guide, The Johns Hopkins University, 2019. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540078/3.1/Capnocytophaga_spp_.
Auwaerter P. Capnocytophaga spp. Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540078/3.1/Capnocytophaga_spp_. Accessed April 20, 2021.
Auwaerter, P. (2019). Capnocytophaga spp. In Johns Hopkins ABX Guide. The Johns Hopkins University. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540078/3.1/Capnocytophaga_spp_
Auwaerter P. Capnocytophaga Spp [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. [cited 2021 April 20]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540078/3.1/Capnocytophaga_spp_.
* Article titles in AMA citation format should be in sentence-case
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