Johns Hopkins ABX Guide
Bacterial Meningitis, Adult Acute Community-acquired
Bacterial Meningitis, Adult Acute Community-acquired is a topic covered in the Johns Hopkins ABX Guide.
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PATHOGENS
- S. pneumoniae
- N. meningitidis
- Listeria monocytogenes
- Haemophilus influenzae
- Streptococcus agalactiae (Group B Streptococcus, GBS)
- Enterococcus (uncommon)
- For community-acquired bacterial meningitis, Streptococcus pneumoniae and Neisseria meningitidis are responsible for usually 80% of all adult cases.
- The overall species-specific infection rates (all ages, 1997-2008 data[8]):
- Streptococcus pneumoniae 58%
- Group B streptococcus 18.1%
- Neisseria meningitidis 13.9%
- Haemophilus influenzae 6.7%
- Note the incidence of Haemophilus influenzae type b meningitis in children has been dramatically reduced with the introduction of the vaccine in 1986; most cases of H. influenzae meningitis are secondary to nonserotype b organisms or serotype b infections in non-vaccinated children and adults.
- Listeria monocytogenes 3.4%
- Rates of community-acquired infection with specific pathogens strongly influenced by age.
- Children and young adults 2-29 yrs: N. meningitidis 60%, S. pneumoniae 27%, group B Streptococcus 5%, H. influenzae 5%, L. monocytogenes 2%
- Adults 30-59 yrs: S. pneumoniae 61%, N. meningitidis 18%, H. influenzae 12%, L. monocytogenes 2%
- Adults > 60 yrs: S. pneumoniae 61%, N. meningitidis 18%, H. influenzae 12%, L. monocytogenes 6%, Group B Streptococcus 3%
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PATHOGENS
- S. pneumoniae
- N. meningitidis
- Listeria monocytogenes
- Haemophilus influenzae
- Streptococcus agalactiae (Group B Streptococcus, GBS)
- Enterococcus (uncommon)
- For community-acquired bacterial meningitis, Streptococcus pneumoniae and Neisseria meningitidis are responsible for usually 80% of all adult cases.
- The overall species-specific infection rates (all ages, 1997-2008 data[8]):
- Streptococcus pneumoniae 58%
- Group B streptococcus 18.1%
- Neisseria meningitidis 13.9%
- Haemophilus influenzae 6.7%
- Note the incidence of Haemophilus influenzae type b meningitis in children has been dramatically reduced with the introduction of the vaccine in 1986; most cases of H. influenzae meningitis are secondary to nonserotype b organisms or serotype b infections in non-vaccinated children and adults.
- Listeria monocytogenes 3.4%
- Rates of community-acquired infection with specific pathogens strongly influenced by age.
- Children and young adults 2-29 yrs: N. meningitidis 60%, S. pneumoniae 27%, group B Streptococcus 5%, H. influenzae 5%, L. monocytogenes 2%
- Adults 30-59 yrs: S. pneumoniae 61%, N. meningitidis 18%, H. influenzae 12%, L. monocytogenes 2%
- Adults > 60 yrs: S. pneumoniae 61%, N. meningitidis 18%, H. influenzae 12%, L. monocytogenes 6%, Group B Streptococcus 3%
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Last updated: November 7, 2020
Citation
Auwaerter, Paul. "Bacterial Meningitis, Adult Acute Community-acquired." Johns Hopkins ABX Guide, The Johns Hopkins University, 2020. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540048/all/Bacterial_Meningitis__Adult_Acute_Community_acquired.
Auwaerter P. Bacterial Meningitis, Adult Acute Community-acquired. Johns Hopkins ABX Guide. The Johns Hopkins University; 2020. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540048/all/Bacterial_Meningitis__Adult_Acute_Community_acquired. Accessed March 31, 2023.
Auwaerter, P. (2020). Bacterial Meningitis, Adult Acute Community-acquired. In Johns Hopkins ABX Guide. The Johns Hopkins University. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540048/all/Bacterial_Meningitis__Adult_Acute_Community_acquired
Auwaerter P. Bacterial Meningitis, Adult Acute Community-acquired [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2020. [cited 2023 March 31]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540048/all/Bacterial_Meningitis__Adult_Acute_Community_acquired.
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PB - The Johns Hopkins University
DB - Pediatrics Central
DP - Unbound Medicine
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