Azithromycin
INDICATIONS
FDA
FDA
Systemic
- Community-acquired pneumonia of mild severity (20%-30% of S. pneumoniae strains resistant to azithromycin but clinical significance unknown)
- FDA-approved for adults and children (6 months and older)
- Pharyngitis (adults and children older than 2 years)
- Acute bacterial sinusitis(adults)
- Acute otitis media (pediatric, 6 months of age and older)
- Acute bacterial exacerbations of chronic obstructive pulmonary disease(adults)
- Treatment and prophylaxis of disseminated M. avium infection (treatment requires co-administration with ethambutol)
- Uncomplicated skin and skin structure infections(adults)
- Urethritis and cervicitis (caused by C. trachomatis)
- Please see the modules for the latest recommendations.
- Genital ulcer disease
- Please see the module for the latest recommendations.
Topical
- Bacterial conjunctivitis
- FDA labeling for coryneform group G (efficacy studied in fewer than 10 infections), Haemophilus influenzae, Staphylococcus aureus, Streptococcus mitis group, and Streptococcus pneumoniae.
NON-FDA APPROVED USES
NON-FDA APPROVED USES
It is not a comprehensive listing, but azithromycin is commonly employed in the following:
- Babesiosis (in combination with atovaquone)
- Bartonella
- Diarrhea
- IncludingCampylobacter, traveler’s diarrhea, Shigella
- Toxoplasmosis (with pyrimethamine)
- Meningococcal meningitis prophylaxis
- Falciparum malaria (in combination with artesunate), uncomplicated disease
- Pertussis
- Anti-inflammatory therapy in cystic fibrosis or bronchiectasis
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Last updated: September 11, 2023
Citation
Auwaerter, Paul G, and Paul A Pham. "Azithromycin." Johns Hopkins ABX Guide, The Johns Hopkins University, 2023. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540040/all/Azithromycin.
Auwaerter PG, Pham PA. Azithromycin. Johns Hopkins ABX Guide. The Johns Hopkins University; 2023. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540040/all/Azithromycin. Accessed December 18, 2024.
Auwaerter, P. G., & Pham, P. A. (2023). Azithromycin. In Johns Hopkins ABX Guide. The Johns Hopkins University. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540040/all/Azithromycin
Auwaerter PG, Pham PA. Azithromycin [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2023. [cited 2024 December 18]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540040/all/Azithromycin.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC
T1 - Azithromycin
ID - 540040
A1 - Auwaerter,Paul,M.D.
AU - Pham,Paul,Pharm.D.
Y1 - 2023/09/11/
BT - Johns Hopkins ABX Guide
UR - https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540040/all/Azithromycin
PB - The Johns Hopkins University
DB - Pediatrics Central
DP - Unbound Medicine
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