Johns Hopkins ABX Guide
Anthrax
Anthrax is a topic covered in the Johns Hopkins ABX Guide.
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PATHOGENS
- Bacillus anthracis (Category A bio-terrorism agent)
- Spore is primary infectious form.
- Virulence factors:
- Antiphagocytic capsule
- Exotoxins: why anti-toxin therapies have been developed given the prominence of these toxins in causing illness.
- Edema toxin (ET)
- Lethal toxin (LT)
- Protective antigen (PA) combines ET and LT and facilitates entry into cells and assists in downregulating immune responses.
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PATHOGENS
- Bacillus anthracis (Category A bio-terrorism agent)
- Spore is primary infectious form.
- Virulence factors:
- Antiphagocytic capsule
- Exotoxins: why anti-toxin therapies have been developed given the prominence of these toxins in causing illness.
- Edema toxin (ET)
- Lethal toxin (LT)
- Protective antigen (PA) combines ET and LT and facilitates entry into cells and assists in downregulating immune responses.
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Last updated: March 5, 2019
Citation
Auwaerter, Paul G, and John G Bartlett. "Anthrax." Johns Hopkins ABX Guide, The Johns Hopkins University, 2019. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540028/all/Anthrax.
Auwaerter PG, Bartlett JG. Anthrax. Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540028/all/Anthrax. Accessed January 24, 2020.
Auwaerter, P. G., & Bartlett, J. G. (2019). Anthrax. In Johns Hopkins ABX Guide. Available from https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540028/all/Anthrax
Auwaerter PG, Bartlett JG. Anthrax [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. [cited 2020 January 24]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540028/all/Anthrax.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC
T1 - Anthrax
ID - 540028
A1 - Auwaerter,Paul,M.D.
AU - Bartlett,John,M.D.
Y1 - 2019/03/05/
BT - Johns Hopkins ABX Guide
UR - https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540028/all/Anthrax
PB - The Johns Hopkins University
DB - Pediatrics Central
DP - Unbound Medicine
ER -