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    Anthrax

    Paul G. Auwaerter, M.D., John G. Bartlett, M.D.
    Anthrax is a topic covered in the Johns Hopkins ABX Guide.

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    PATHOGENS

    • Bacillus anthracis (Category A bio-terrorism agent)
    • Spore is primary infectious form.
    • Virulence factors:
      • Antiphagocytic capsule
      • Exotoxins: why anti-toxin therapies have been developed given the prominence of these toxins in causing illness.
        • Edema toxin (ET)
        • Lethal toxin (LT)
        • Protective antigen (PA) combines ET and LT and facilitates entry into cells and assists in downregulating immune responses.

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    Last updated: March 5, 2019

    Citation

    Auwaerter, Paul G, and John G Bartlett. "Anthrax." Johns Hopkins ABX Guide, The Johns Hopkins University, 2019. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540028/all/Anthrax.
    Auwaerter PG, Bartlett JG. Anthrax. Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540028/all/Anthrax. Accessed March 24, 2019.
    Auwaerter, P. G., & Bartlett, J. G. (2019). Anthrax. In Johns Hopkins ABX Guide. Available from https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540028/all/Anthrax
    Auwaerter PG, Bartlett JG. Anthrax [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. [cited 2019 March 24]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540028/all/Anthrax.
    * Article titles in AMA citation format should be in sentence-case
    TY - ELEC T1 - Anthrax ID - 540028 A1 - Auwaerter,Paul,M.D. AU - Bartlett,John,M.D. Y1 - 2019/03/05/ BT - Johns Hopkins ABX Guide UR - https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540028/all/Anthrax PB - The Johns Hopkins University DB - Pediatrics Central DP - Unbound Medicine ER -