Anthrax, cutaneous is a topic covered in the Johns Hopkins ABX Guide.

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PATHOGENS

  • Bacillus anthracis
    • B. anthracis is a gram-positive spore-forming bacillus that may remain stable in the environment for decades.
      • On Gram stain, rods form filamentous-like strands [Fig 1].
    • Pathogenesis results from spore entry via skin (cutaneous anthrax) or lungs (inhalation anthrax)
      • The vegetative form cause disease due to toxin production: Protective antigen (PA) which combines with edema factor (EF) to form edema toxin (ET) and with PA to form lethal toxin (LT)

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Last updated: March 5, 2019