Johns Hopkins ABX Guide
Anthrax, cutaneous
Anthrax, cutaneous is a topic covered in the Johns Hopkins ABX Guide.
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PATHOGENS
- Bacillus anthracis
- B. anthracis is a gram-positive spore-forming bacillus that may remain stable in the environment for decades.
- On Gram stain, rods form filamentous-like strands [Fig 1].
- Pathogenesis results from spore entry via skin (cutaneous anthrax) or lungs (inhalation anthrax)
- The vegetative form cause disease due to toxin production: Protective antigen (PA) which combines with edema factor (EF) to form edema toxin (ET) and with PA to form lethal toxin (LT)
- B. anthracis is a gram-positive spore-forming bacillus that may remain stable in the environment for decades.
-- To view the remaining sections of this topic, please sign in or purchase a subscription --
PATHOGENS
- Bacillus anthracis
- B. anthracis is a gram-positive spore-forming bacillus that may remain stable in the environment for decades.
- On Gram stain, rods form filamentous-like strands [Fig 1].
- Pathogenesis results from spore entry via skin (cutaneous anthrax) or lungs (inhalation anthrax)
- The vegetative form cause disease due to toxin production: Protective antigen (PA) which combines with edema factor (EF) to form edema toxin (ET) and with PA to form lethal toxin (LT)
- B. anthracis is a gram-positive spore-forming bacillus that may remain stable in the environment for decades.
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Last updated: March 5, 2019
Citation
Auwaerter, Paul G, and John G Bartlett. "Anthrax, Cutaneous." Johns Hopkins ABX Guide, The Johns Hopkins University, 2019. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540027/all/Anthrax__cutaneous.
Auwaerter PG, Bartlett JG. Anthrax, cutaneous. Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540027/all/Anthrax__cutaneous. Accessed January 20, 2020.
Auwaerter, P. G., & Bartlett, J. G. (2019). Anthrax, cutaneous. In Johns Hopkins ABX Guide. Available from https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540027/all/Anthrax__cutaneous
Auwaerter PG, Bartlett JG. Anthrax, Cutaneous [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. [cited 2020 January 20]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540027/all/Anthrax__cutaneous.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC
T1 - Anthrax, cutaneous
ID - 540027
A1 - Auwaerter,Paul,M.D.
AU - Bartlett,John,M.D.
Y1 - 2019/03/05/
BT - Johns Hopkins ABX Guide
UR - https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540027/all/Anthrax__cutaneous
PB - The Johns Hopkins University
DB - Pediatrics Central
DP - Unbound Medicine
ER -