Trypanosoma brucei gambiense/rhodesiense
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MICROBIOLOGY
- Protozoan hemoflagellate, agent of human African sleeping sickness.
- Trypanosoma brucei complex of which two subspecies exist:
- T. b. gambiense causes West African sleeping sickness
- T. b. rhodesiense causes East African sleeping sickness
- Trypanosomes, zoonotic infection of cattle and other animals, transmitted by the painful bite of TseTse fly (Fig 1, not preventable with DEET) usually in rural African locales.
- Trypanosoma brucei gambiense (g-HAT): humans only known significant reservoir, hence efforts for eradication.
- Other modes of transmission possible: but probably rare, vertical (mother → child), sexual contact, laboratory-related, blood transfusion, organ transplantation.
- Trypanosoma brucei rhodesiense (t-HAT): domesticated and wild animals may be reservoirs.
- Trypanosoma brucei gambiense (g-HAT): humans only known significant reservoir, hence efforts for eradication.
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MICROBIOLOGY
- Protozoan hemoflagellate, agent of human African sleeping sickness.
- Trypanosoma brucei complex of which two subspecies exist:
- T. b. gambiense causes West African sleeping sickness
- T. b. rhodesiense causes East African sleeping sickness
- Trypanosomes, zoonotic infection of cattle and other animals, transmitted by the painful bite of TseTse fly (Fig 1, not preventable with DEET) usually in rural African locales.
- Trypanosoma brucei gambiense (g-HAT): humans only known significant reservoir, hence efforts for eradication.
- Other modes of transmission possible: but probably rare, vertical (mother → child), sexual contact, laboratory-related, blood transfusion, organ transplantation.
- Trypanosoma brucei rhodesiense (t-HAT): domesticated and wild animals may be reservoirs.
- Trypanosoma brucei gambiense (g-HAT): humans only known significant reservoir, hence efforts for eradication.
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