Hypogammaglobulinemia
Basics
Description
- A disorder of the humoral immune system characterized by deficient or absent immunoglobulins and the inability to produce specific antibody
- Subtypes include primary immunodeficiency and secondary deficiency due to other extrinsic disease (i.e., malignancy).
Epidemiology
Incidence and prevalence depends on underlying defect or cause. Antibody deficiency syndromes represent ~70% of primary immune deficiencies.
Risk Factors
Genetic defects have been identified in many cases (see “Differential Diagnosis”).
There's more to see -- the rest of this topic is available only to subscribers.
Citation
Cabana, Michael D., editor. "Hypogammaglobulinemia." 5-Minute Pediatric Consult, 8th ed., Wolters Kluwer, 2019. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/5-Minute-Pediatric-Consult/617670/all/Hypogammaglobulinemia.
Hypogammaglobulinemia. In: Cabana MDM, ed. 5-Minute Pediatric Consult. Wolters Kluwer; 2019. https://peds.unboundmedicine.com/pedscentral/view/5-Minute-Pediatric-Consult/617670/all/Hypogammaglobulinemia. Accessed November 7, 2024.
Hypogammaglobulinemia. (2019). In Cabana, M. D. (Ed.), 5-Minute Pediatric Consult (8th ed.). Wolters Kluwer. https://peds.unboundmedicine.com/pedscentral/view/5-Minute-Pediatric-Consult/617670/all/Hypogammaglobulinemia
Hypogammaglobulinemia [Internet]. In: Cabana MDM, editors. 5-Minute Pediatric Consult. Wolters Kluwer; 2019. [cited 2024 November 07]. Available from: https://peds.unboundmedicine.com/pedscentral/view/5-Minute-Pediatric-Consult/617670/all/Hypogammaglobulinemia.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC
T1 - Hypogammaglobulinemia
ID - 617670
ED - Cabana,Michael D,
BT - 5-Minute Pediatric Consult
UR - https://peds.unboundmedicine.com/pedscentral/view/5-Minute-Pediatric-Consult/617670/all/Hypogammaglobulinemia
PB - Wolters Kluwer
ET - 8
DB - Pediatrics Central
DP - Unbound Medicine
ER -