Hypogammaglobulinemia

Hypogammaglobulinemia is a topic covered in the 5-Minute Pediatric Consult.

To view the entire topic, please or purchase a subscription.

Pediatrics Central™ is an all-in-one application that puts valuable medical information, via your mobile device or the web, in the hands of clinicians treating infants, children, and adolescents. Explore these free sample topics:

Pediatrics Central

-- The first section of this topic is shown below --

Basics

Description

  • A disorder of the humoral immune system characterized by deficient or absent immunoglobulins and the inability to produce specific antibody
  • Subtypes include primary immunodeficiency and secondary deficiency due to other extrinsic disease (i.e., malignancy).

Epidemiology

Incidence and prevalence depends on underlying defect or cause. Antibody deficiency syndromes represent ~70% of primary immune deficiencies.

Risk Factors

Genetic defects have been identified in many cases (see “Differential Diagnosis”).

-- To view the remaining sections of this topic, please or purchase a subscription --