Pediatrics Central™ is an all-in-one application that puts valuable medical information, via your mobile device or the web, in the hands of clinicians treating infants, children, and adolescents. Explore these free sample topics:
-- The first section of this topic is shown below --
- A disorder of the humoral immune system characterized by deficient or absent immunoglobulins and the inability to produce specific antibody
- Subtypes include primary immunodeficiency and secondary deficiency due to other extrinsic disease (i.e., malignancy).
Incidence and prevalence depends on underlying defect or cause. Antibody deficiency syndromes represent ~70% of primary immune deficiencies.
Genetic defects have been identified in many cases (see “Differential Diagnosis”).