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Pallor is a topic covered in the 5-Minute Pediatric Consult.

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  • Pallor is defined as paleness of the skin and may be a reflection of anemia or poor peripheral perfusion.
  • The normal range for hemoglobin is age-dependent.
  • Anemia can be defined functionally as the inability of hemoglobin to meet cellular oxygen demand.
  • Parents often fail to notice pallor of gradual onset.
    • Grandparents or others who see the child less often may be the first to suspect pallor.

Risk Factors

  • Ages between 6 months and 3 years or adolescent females
    • Peak age ranges for iron deficiency
  • Gender
    • Some red cell–enzyme X-linked defects such as glucose-6-phosphate dehydrogenase (G6PD) and phosphoglycerate kinase deficiencies are sex linked.
  • Race
    • African: hemoglobins S and C, α- and β-thalassemia trait, G6PD deficiency
    • Southeast Asian: hemoglobin E and α-thalassemia
    • Mediterranean descent: β-thalassemia and G6PD deficiency


Familial history: Some of the congenital hemolytic anemias are autosomal dominant.

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Cabana, Michael D., editor. "Pallor." 5-Minute Pediatric Consult, 8th ed., Wolters Kluwer, 2019. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/5-Minute-Pediatric-Consult/617492/all/Pallor.
Pallor. In: Cabana MD, ed. 5-Minute Pediatric Consult. 8th ed. Wolters Kluwer; 2019. https://peds.unboundmedicine.com/pedscentral/view/5-Minute-Pediatric-Consult/617492/all/Pallor. Accessed April 19, 2019.
Pallor. (2019). In Cabana, M. D. (Ed.), 5-Minute Pediatric Consult. Available from https://peds.unboundmedicine.com/pedscentral/view/5-Minute-Pediatric-Consult/617492/all/Pallor
Pallor [Internet]. In: Cabana MD, editors. 5-Minute Pediatric Consult. Wolters Kluwer; 2019. [cited 2019 April 19]. Available from: https://peds.unboundmedicine.com/pedscentral/view/5-Minute-Pediatric-Consult/617492/all/Pallor.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Pallor ID - 617492 ED - Cabana,Michael D, BT - 5-Minute Pediatric Consult UR - https://peds.unboundmedicine.com/pedscentral/view/5-Minute-Pediatric-Consult/617492/all/Pallor PB - Wolters Kluwer ET - 8 DB - Pediatrics Central DP - Unbound Medicine ER -