Floppy Infant Syndrome

Floppy Infant Syndrome is a topic covered in the 5-Minute Pediatric Consult.

To view the entire topic, please or purchase a subscription.

Pediatrics Central™ is an all-in-one application that puts valuable medical information, via your mobile device or the web, in the hands of clinicians treating infants, children, and adolescents. Explore these free sample topics:

Pediatrics Central

-- The first section of this topic is shown below --

Basics

Description

  • “Floppy infant” refers to the newborn/infant presenting at birth or early in life with hypotonia, a symptom of diminished tone of skeletal muscles associated with decreased resistance of muscles to passive stretching.
  • Hypotonia can be caused by abnormalities of the CNS (central hypotonia), peripheral neuromuscular system (peripheral hypotonia), or combined abnormality involving both (combined hypotonia).
  • Nonspecific transient hypotonia occurs in nonneurologic conditions and may suggest gastrointestinal (GI), cardiac, pulmonary, infectious, renal, or endocrine disease.

Epidemiology

No comprehensive prevalence known, owing to presence of hypotonia as a feature of many distinct disorders; overall, central hypotonia is more common than peripheral hypotonia.

Risk Factors

Genetics

Substantial proportion (>50%) of infantile hypotonia cases accounted for by genetic-metabolic disorders.

Etiology

Causes may be divided into two major categories:

  • Central: hypotonia with decreased alertness, developmental delay, and lack of (or minimal) weakness; caused by upper motor neuron defect
  • Peripheral: hypotonia with weakness, paucity of antigravity movements, decreased or absent deep tendon reflexes (DTRs), and visual alertness; caused by lower motor neuron defect (i.e., disorders of anterior horn cell, peripheral nerve, neuromuscular junction, or skeletal muscle)

Commonly Associated Conditions

  • Respiratory problems (apnea/hypoventilation)
  • Feeding/swallowing difficulties
  • Hip dislocation/contractures/joint laxity
  • Seizure disorder
  • Cognitive/developmental delay
  • Hypersomnolence

-- To view the remaining sections of this topic, please or purchase a subscription --

Citation

* When formatting your citation, note that all book, journal, and database titles should be italicized* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Floppy Infant Syndrome ID - 617038 ED - Cabana,Michael D, BT - 5-Minute Pediatric Consult UR - https://peds.unboundmedicine.com/pedscentral/view/5-Minute-Pediatric-Consult/617038/all/Floppy_Infant_Syndrome PB - Wolters Kluwer ET - 8 DB - Pediatrics Central DP - Unbound Medicine ER -