Oropouche virus
MICROBIOLOGY
- Oropouche virus (OROV) is a zoonotic arbovirus that infects animals and humans. It is borne by biting midges and possibly mosquitoes.
- Single-strand, segmented (3), negative-sense RNA virus is a member of the Orthobunyavirus genus.
- OROV reassortants described causing human infection, including Madre de Dios and Iquitos viruses.
- Reservoir: non-human primates, wild birds and sloths
- The transmission cycle is poorly understood; perhaps other reservoirs are not yet described.
- Main vectors: biting midges, small blood-sucking flies (Culicoides paraensis)--also known as no-see-ums--are likely the primary vector (bite most vigorously at dusk and dawn but can bite throughout the night and during the day); also, mosquitoes that bite primarily from dusk until dawn (Culex quinquefasciatus, Coquillettidia venezuelensis, and Aedes serratus)
- Evidence from Brazil strongly supports that vertical transmission can occur with a risk of pregnancy wastage.
- Single-strand, segmented (3), negative-sense RNA virus is a member of the Orthobunyavirus genus.
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Last updated: October 27, 2024
Citation
Auwaerter, Paul G. "Oropouche Virus." Johns Hopkins ABX Guide, The Johns Hopkins University, 2024. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540796/all/Oropouche_virus.
Auwaerter PG. Oropouche virus. Johns Hopkins ABX Guide. The Johns Hopkins University; 2024. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540796/all/Oropouche_virus. Accessed December 7, 2024.
Auwaerter, P. G. (2024). Oropouche virus. In Johns Hopkins ABX Guide. The Johns Hopkins University. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540796/all/Oropouche_virus
Auwaerter PG. Oropouche Virus [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2024. [cited 2024 December 07]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540796/all/Oropouche_virus.
* Article titles in AMA citation format should be in sentence-case
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