- Gram-negative bacillus, aerobic, on staining, may be highly pleomorphic.
- Part of upper respiratory human flora and occasionally on oral mucosal surfaces can be recovered in 70% of normal people.
- Catalase-negative, oxidase-positive, indole-positive.
- Slow-growing in traditional media, e.g., blood agar.
- Low-virulence organism
- Member of HACEK group that may cause endocarditis
- Haemophilus species, Aggregatibacter species, Cardiobacterium hominis, Eikenella corrodens and Kingella species
- Major species: Cardiobacterium hominis is the most common human pathogen species, though it remains a rare infection overall.
- Other species:
- C. valvarum
- MALDI-ToF has helped improve proper microbiologic identification.
- Other species:
- Traditionally, a penicillin-sensitive organism, though in recent years, beta-lactamase production has been described in some isolates.
- Aminoglycosides and fluoroquinolones are also usually active.
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Last updated: January 18, 2023
Auwaerter, Paul G. "Cardiobacterium Species." Johns Hopkins ABX Guide, The Johns Hopkins University, 2023. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540710/all/Cardiobacterium_species.
Auwaerter PG. Cardiobacterium species. Johns Hopkins ABX Guide. The Johns Hopkins University; 2023. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540710/all/Cardiobacterium_species. Accessed June 4, 2023.
Auwaerter, P. G. (2023). Cardiobacterium species. In Johns Hopkins ABX Guide. The Johns Hopkins University. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540710/all/Cardiobacterium_species
Auwaerter PG. Cardiobacterium Species [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2023. [cited 2023 June 04]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540710/all/Cardiobacterium_species.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Cardiobacterium species ID - 540710 A1 - Auwaerter,Paul,M.D. Y1 - 2023/01/18/ BT - Johns Hopkins ABX Guide UR - https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540710/all/Cardiobacterium_species PB - The Johns Hopkins University DB - Pediatrics Central DP - Unbound Medicine ER -