Paracoccidioides brasiliensis
MICROBIOLOGY
- Dimorphic fungus.
- At 37°C appears as an oval to round yeast cell variable in size, 4-40 μm.
- The classic "ship’s wheel" structure [Fig 1] represents a mother cell surrounded by narrow-based budding daughter cells.
- Four phylogenetic species (S1, PS2, PS3, PS4) are confined to particular endemic regions.
- Autochthonous disease from southern Mexico to northern Argentina.
- Countries where there have been no reports of paracoccidioidomycosis (PM), include:
- Central America: Belize and Nicaragua
- South America: Chile, French Guiana, Guiana, and Suriname
- Countries where there have been no reports of paracoccidioidomycosis (PM), include:
- Paracoccidioides lutzzi causes a similar disease in humans; cases due to P. lutzzi have only been reported in Brazil and Ecuador.
- Other species described now with molecular taxonomy infecting humans:
- Several cryptic species, including Paracoccidioides americana, P. restrepiensis, and P. venezuelensis.
- Preference for cutaneous and mucous membranes.
- Other species described now with molecular taxonomy infecting humans:
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Last updated: February 4, 2023
Citation
Fabre, Valeria. "Paracoccidioides Brasiliensis." Johns Hopkins ABX Guide, The Johns Hopkins University, 2023. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540662/all/Paracoccidioides_brasiliensis.
Fabre V. Paracoccidioides brasiliensis. Johns Hopkins ABX Guide. The Johns Hopkins University; 2023. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540662/all/Paracoccidioides_brasiliensis. Accessed October 13, 2024.
Fabre, V. (2023). Paracoccidioides brasiliensis. In Johns Hopkins ABX Guide. The Johns Hopkins University. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540662/all/Paracoccidioides_brasiliensis
Fabre V. Paracoccidioides Brasiliensis [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2023. [cited 2024 October 13]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540662/all/Paracoccidioides_brasiliensis.
* Article titles in AMA citation format should be in sentence-case
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T1 - Paracoccidioides brasiliensis
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A1 - Fabre,Valeria,M.D.
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BT - Johns Hopkins ABX Guide
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PB - The Johns Hopkins University
DB - Pediatrics Central
DP - Unbound Medicine
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