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Urethritis [Men]

Valeria Fabre, M.D.
Urethritis [Men] is a topic covered in the Johns Hopkins ABX Guide.

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  • Commonly implicated:
    • Chlamydia trachomatis (CT) : most frequent cause of urethritis in men accounting for 23%-55% of cases. However, the proportion of non-gonococcal urethritis (NGU) cases due to CT is declining gradually.
    • Mycoplasma genitalium: may be the second most frequent cause of urethritis in the U.S and U.K. May account for between 15%-22% of cases of acute NGU. Also has a role in chronic NGU.
    • Neisseria gonorrhoeae: as a cause of urethritis, gonorrhea is increasingly a geographically isolated infection in the US. It persists in inner-city populations, in particular.
    • Trichomonas vaginalis: is the cause of only about 2% of cases of acute NGU but probably a higher proportion of chronic NGU.
    • Ureaplasma urealyticum: biovar 2 is probably a more important cause of acute NGU than previously realized. In 1999 the organism was divided into 2 species: U. parnumparnum (Biovar 1) and U. urealyticum (Biovar 2). Studies suggest only the latter associated with urethritis.
  • Less common: include
    • Herpes simplex virus (rare in absence of obvious skin lesions)
    • Adenovirus
    • Haemophilus spp
    • Yeasts, e.g., Candida spp.
    • N. meningitidis 
    • Staphylococcus saprophyticus.  
    • Novel bacteria recently associated with bacterial vaginosis such as Leptotrichia/Sneathia spp. may be the urethral pathogens of "idiopathic" NGU[7].

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Last updated: November 30, 2015


Fabre, Valeria. "Urethritis [Men]." Johns Hopkins ABX Guide, The Johns Hopkins University, 2015. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540571/all/Urethritis_[Men].
Fabre V. Urethritis [Men]. Johns Hopkins ABX Guide. The Johns Hopkins University; 2015. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540571/all/Urethritis_[Men]. Accessed April 20, 2019.
Fabre, V. (2015). Urethritis [Men]. In Johns Hopkins ABX Guide. Available from https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540571/all/Urethritis_[Men]
Fabre V. Urethritis [Men] [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2015. [cited 2019 April 20]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540571/all/Urethritis_[Men].
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Urethritis [Men] ID - 540571 A1 - Fabre,Valeria,M.D. Y1 - 2015/11/30/ BT - Johns Hopkins ABX Guide UR - https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540571/all/Urethritis_[Men] PB - The Johns Hopkins University DB - Pediatrics Central DP - Unbound Medicine ER -