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SARS [Severe Acute Respiratory Syndrome]

Paul G. Auwaerter, M.D., Trish Perl, M.D.
SARS [Severe Acute Respiratory Syndrome] is a topic covered in the Johns Hopkins ABX Guide.

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  • SARS-associated coronavirus (SARS-CoV). Respiratory pathogen with spread by airborne droplet transmission.
    • RNA enveloped virus; note that the coronavirus causing SARS is a separate group than those previously reported to cause human or animal illness.
    • First reported in SE Asia February 2003. Last known human case in China, April 2004.
    • Declared a select agent by CDC (2012, select agent is a bacterium, virus or toxin that has the potential to pose a severe threat to public health and safety).
  • Although Coronavirus and metapneumovirus and other bacterial and viral (influenza) pathogens have also been co-isolated from patients, SARS-CoV is considered the causative agent.
  • Animal reservoir initially thought to be the civet cat, latest information suggests the Horseshoe bat implicated in transmitting this infection to humans.

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Last updated: June 7, 2017


Auwaerter, Paul G, and Trish Perl. "SARS [Severe Acute Respiratory Syndrome]." Johns Hopkins ABX Guide, The Johns Hopkins University, 2017. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540494/all/SARS_[Severe_Acute_Respiratory_Syndrome].
Auwaerter PG, Perl T. SARS [Severe Acute Respiratory Syndrome]. Johns Hopkins ABX Guide. The Johns Hopkins University; 2017. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540494/all/SARS_[Severe_Acute_Respiratory_Syndrome]. Accessed April 19, 2019.
Auwaerter, P. G., & Perl, T. (2017). SARS [Severe Acute Respiratory Syndrome]. In Johns Hopkins ABX Guide. Available from https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540494/all/SARS_[Severe_Acute_Respiratory_Syndrome]
Auwaerter PG, Perl T. SARS [Severe Acute Respiratory Syndrome] [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2017. [cited 2019 April 19]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540494/all/SARS_[Severe_Acute_Respiratory_Syndrome].
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - SARS [Severe Acute Respiratory Syndrome] ID - 540494 A1 - Auwaerter,Paul,M.D. AU - Perl,Trish,M.D. Y1 - 2017/06/07/ BT - Johns Hopkins ABX Guide UR - https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540494/all/SARS_[Severe_Acute_Respiratory_Syndrome] PB - The Johns Hopkins University DB - Pediatrics Central DP - Unbound Medicine ER -