- All forms of tuberculosis.
- Treatment of asymptomatic carriers of Neisseria meningitidis to eliminate meningococci from the nasopharynx.
NON-FDA APPROVED USES
- Prosthetic valve endocarditis caused by staphylococci in combination with other agents (e.g. oxacillin/nafcillin, vancomycin) after blood cultures have cleared.
- Prosthetic joint infections following debridement and retention of the prosthesis or 1-stage exchange.
- Meningitis caused by penicillin and ceftriaxone resistant S. pneumoniae
- Non-tuberculous mycobacterial infections (e.g. leprosy, MAC)
- Bartonella infections
- Q-fever and rickettsialinfections
- Cutaneous leishmaniasis
- Legionella infections
- Anthrax infections
- NOTE: Rifampin is usually used in combination with other agents due to quick emergence of resistance if used as monotherapy.
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