Cutibacterium (Propionibacterium) species

Cutibacterium (Propionibacterium) species is a topic covered in the Johns Hopkins ABX Guide.

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MICROBIOLOGY

  • Previously termed Proprionibacterium
    • Major human pathogens: many species, generally the two below represent majority of isolates. Member of Proprionibacteriaeceae.
      • Cutibacterium acnes 
      • Cutibacterium avidum 
  • Gram-positive pleomorphic rod that grows best anaerobically [Fig].
  • Usually inhabits human skin, sebaceous glands, nasopharynx, GI/GU tracts.
  • Generally sensitive to beta-lactams and resistant to aminoglycosides.
  • Slow growth, often >5-6d.
  • Reclassification of Proprionibacterium species as originally described due to the bacteria producing propionic acid as fermentation product. Bacteria seen in wide range of conditions: including cheeses (Swiss), ruminants stomachs, human skin. Based on 16s ribosomal analysis, this is now divided into the following:
    • Acidipropionibacterium gen. nov.
    • Cutibacterium gen nov.
    • Pseudopropionibacteriumg en. nov.
    • Propionibacterium (amended description of the genus)

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Last updated: December 6, 2017