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Miltefosine

Kathryn Dzintars, Pharm.D., BCPS, Paul A. Pham, Pharm.D.
Miltefosine is a topic covered in the Johns Hopkins ABX Guide.

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INDICATIONS

FDA

  • Miltefosine is available under an expanded access IND form the CDC (770-488-7100) in the U.S. for the treatment of free-living ameba, including primary meningoencephalitis (PAM) caused by Naegleria fowleri and granulomatous amebic encephalitis (GAM) caused by Balamuthia mandrillaris and Acanthamoeba species.
  • Treatment of cutaneous, mucosal, and visceral leishmaniasis in patients >12 years of age.

NON-FDA APPROVED USES

  • Use in combination with voriconazole and terbinafine for the management of Scedosporium prolificans

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Last updated: April 5, 2016

Citation

Dzintars, Kathryn, and Paul A Pham. "Miltefosine." Johns Hopkins ABX Guide, The Johns Hopkins University, 2016. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540350/all/Miltefosine.
Dzintars K, Pham PA. Miltefosine. Johns Hopkins ABX Guide. The Johns Hopkins University; 2016. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540350/all/Miltefosine. Accessed June 25, 2019.
Dzintars, K., & Pham, P. A. (2016). Miltefosine. In Johns Hopkins ABX Guide. Available from https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540350/all/Miltefosine
Dzintars K, Pham PA. Miltefosine [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2016. [cited 2019 June 25]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540350/all/Miltefosine.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Miltefosine ID - 540350 A1 - Dzintars,Kathryn,Pharm.D., BCPS AU - Pham,Paul,Pharm.D. Y1 - 2016/04/05/ BT - Johns Hopkins ABX Guide UR - https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540350/all/Miltefosine PB - The Johns Hopkins University DB - Pediatrics Central DP - Unbound Medicine ER -