Johns Hopkins ABX Guide
Giardia lamblia
Giardia lamblia is a topic covered in the Johns Hopkins ABX Guide.
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MICROBIOLOGY
- Giardia lamblia (syn. G. duodenalis or G. intestinalis)
- Flagellated bi-nucleated protozoan (see figure)
- Most common intestinal parasite in North America.
- CDC image gallery at https://www.cdc.gov/dpdx/giardiasis/index.html.
- Life cycle forms are: 1) highly infectious cysts, and 2) disease-causing trophozoites.
- Following excystation, trophozoites multiply and colonize the upper small intestine.
- Trophozoites with flat ventral surface adhere to brush border of enterocytes and cause malabsorption.[7]
- Transmitted by contaminated water, food, person-to-person, and fecal-oral contact.[6]
- Surface water is easily contaminated by cysts shed from mammalian hosts such as beaver, sheep, cattle, dogs, or cats.
- Highly contagious, low infective dose of 10 cysts.
- Occurs worldwide, specifically in settings of daycare centers, over-crowded areas with poor sanitation, and outdoor recreation or swimming pools.[6]
-- To view the remaining sections of this topic, please log in or purchase a subscription --
MICROBIOLOGY
- Giardia lamblia (syn. G. duodenalis or G. intestinalis)
- Flagellated bi-nucleated protozoan (see figure)
- Most common intestinal parasite in North America.
- CDC image gallery at https://www.cdc.gov/dpdx/giardiasis/index.html.
- Life cycle forms are: 1) highly infectious cysts, and 2) disease-causing trophozoites.
- Following excystation, trophozoites multiply and colonize the upper small intestine.
- Trophozoites with flat ventral surface adhere to brush border of enterocytes and cause malabsorption.[7]
- Transmitted by contaminated water, food, person-to-person, and fecal-oral contact.[6]
- Surface water is easily contaminated by cysts shed from mammalian hosts such as beaver, sheep, cattle, dogs, or cats.
- Highly contagious, low infective dose of 10 cysts.
- Occurs worldwide, specifically in settings of daycare centers, over-crowded areas with poor sanitation, and outdoor recreation or swimming pools.[6]
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Last updated: September 10, 2018
Citation
Spacek, Lisa A. "Giardia Lamblia." Johns Hopkins ABX Guide, The Johns Hopkins University, 2018. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540246/all/Giardia_lamblia.
Spacek LA. Giardia lamblia. Johns Hopkins ABX Guide. The Johns Hopkins University; 2018. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540246/all/Giardia_lamblia. Accessed January 25, 2021.
Spacek, L. A. (2018). Giardia lamblia. In Johns Hopkins ABX Guide. The Johns Hopkins University. Retrieved January 25, 2021, from https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540246/all/Giardia_lamblia
Spacek LA. Giardia Lamblia [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2018. [cited 2021 January 25]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540246/all/Giardia_lamblia.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC
T1 - Giardia lamblia
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A1 - Spacek,Lisa,M.D., Ph.D.
Y1 - 2018/09/10/
BT - Johns Hopkins ABX Guide
UR - https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540246/all/Giardia_lamblia
PB - The Johns Hopkins University
DB - Pediatrics Central
DP - Unbound Medicine
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