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Bacteroides fragilis

John G. Bartlett, M.D., Valeria Fabre, M.D.
Bacteroides fragilis is a topic covered in the Johns Hopkins ABX Guide.

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  • Small, pleomorphic Gram-negative anaerobic bacillus
    • Of all species, B. fragilis causes most human Bacteroides infections.
  • Other members of B. fragilis group include:
    • Bacteroides distasonis 
    • Bacteroides ovatus 
    • Bacteroides thetaiotaomicron 
    • Bacteroides vulgatus 
  • Easily grown relative to other anaerobes
  • Colonizes virtually all human colons
  • Organism possibly important in the gut for immune modulation.
  • B. fragilis group almost always susceptible to metronidazole, carbapenems, beta-lactam/beta-lactamase inhibitors

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Last updated: February 6, 2019


Bartlett, John G, and Valeria Fabre. "Bacteroides Fragilis." Johns Hopkins ABX Guide, The Johns Hopkins University, 2019. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540052/all/Bacteroides_fragilis.
Bartlett JG, Fabre V. Bacteroides fragilis. Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540052/all/Bacteroides_fragilis. Accessed April 20, 2019.
Bartlett, J. G., & Fabre, V. (2019). Bacteroides fragilis. In Johns Hopkins ABX Guide. Available from https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540052/all/Bacteroides_fragilis
Bartlett JG, Fabre V. Bacteroides Fragilis [Internet]. In: Johns Hopkins ABX Guide. The Johns Hopkins University; 2019. [cited 2019 April 20]. Available from: https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540052/all/Bacteroides_fragilis.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Bacteroides fragilis ID - 540052 A1 - Bartlett,John,M.D. AU - Fabre,Valeria,M.D. Y1 - 2019/02/06/ BT - Johns Hopkins ABX Guide UR - https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540052/all/Bacteroides_fragilis PB - The Johns Hopkins University DB - Pediatrics Central DP - Unbound Medicine ER -