Tendinopathy

Descriptive text is not available for this imageBASICS

DESCRIPTION

  • Tendinopathy: spectrum of changes in damaged and diseased tendons, resulting in pain and reduced function
  • Tendonitis: acute inflammation of a tendon
  • Tendinosis: chronic degenerative changes in tendon structure

EPIDEMIOLOGY

  • Increases with age and time of puberty
  • Prevalence is higher in boys—in children and adolescents
  • Upper extremity: rotator cuff, medial (flexor tendon) and lateral (extensor tendon) epicondylitis
  • Lower extremity: gluteal tendon, patellar tendon, tibialis posterior tendon, peroneal tendon, Achilles tendon

ETIOLOGY

Typically, repetitive motion/overuse activities

RISK FACTORS

  • Sport- and occupation-specific
  • Sudden increase in activity or initiation of new activity
  • Conditions:
    • Age
    • Family history
    • Diabetes mellitus
    • Hyperlipidemia
    • Obesity
    • Hypermobility
    • Rheumatologic conditions
    • Renal disease
  • Medications:
    • Fluoroquinolones
    • Hormone replacement therapy
    • Statins
    • Corticosteroids
  • Genetics: Multiple genes play a role in tendon health.

PATHOPHYSIOLOGY

  • Decreased tenocyte volume, increase in type III collagen fibers rather than the organized type I collagen, gradual accumulation of tendon matrix damage
  • Inflammation, microtearing, neovascularization, and neoinnervation may be present.

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