5-Minute Pediatric Consult
4p syndrome (Wolf-Hirschhorn syndrome; deletion 4p; monosomy 4p)
MIM 194190; characterized by growth failure of prenatal onset, microcephaly, “Greek helmet” facies (high forehead, prominent glabella, arched eyebrows, straight nose), hypertelorism, hypotonia, neurocognitive impairment, seizures, scoliosis
© Wolters Kluwer Health Lippincott Williams & Wilkins
Citation
Cabana, Michael D., editor. "4p Syndrome (Wolf-Hirschhorn Syndrome; Deletion 4p; Monosomy 4p)." 5-Minute Pediatric Consult, 9th ed., Wolters Kluwer, 2025. Pediatrics Central, peds.unboundmedicine.com/pedscentral/view/5-Minute-Pediatric-Consult/617947/all/4p_syndrome__Wolf_Hirschhorn_syndrome.
4p syndrome (Wolf-Hirschhorn syndrome; deletion 4p; monosomy 4p). In: Cabana MDM, ed. 5-Minute Pediatric Consult. Wolters Kluwer; 2025. https://peds.unboundmedicine.com/pedscentral/view/5-Minute-Pediatric-Consult/617947/all/4p_syndrome__Wolf_Hirschhorn_syndrome. Accessed June 10, 2026.
4p syndrome (Wolf-Hirschhorn syndrome; deletion 4p; monosomy 4p). (2025). In Cabana, M. D. (Ed.), 5-Minute Pediatric Consult (9th ed.). Wolters Kluwer. https://peds.unboundmedicine.com/pedscentral/view/5-Minute-Pediatric-Consult/617947/all/4p_syndrome__Wolf_Hirschhorn_syndrome
4p Syndrome (Wolf-Hirschhorn Syndrome; Deletion 4p; Monosomy 4p) [Internet]. In: Cabana MDM, editors. 5-Minute Pediatric Consult. Wolters Kluwer; 2025. [cited 2026 June 10]. Available from: https://peds.unboundmedicine.com/pedscentral/view/5-Minute-Pediatric-Consult/617947/all/4p_syndrome__Wolf_Hirschhorn_syndrome.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC
T1 - 4p syndrome (Wolf-Hirschhorn syndrome; deletion 4p; monosomy 4p)
ID - 617947
ED - Cabana,Michael D,
BT - 5-Minute Pediatric Consult
UR - https://peds.unboundmedicine.com/pedscentral/view/5-Minute-Pediatric-Consult/617947/all/4p_syndrome__Wolf_Hirschhorn_syndrome
PB - Wolters Kluwer
ET - 9
DB - Pediatrics Central
DP - Unbound Medicine
ER -
