Tecovirimat

Tecovirimat is a topic covered in the Johns Hopkins ABX Guide.

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INDICATIONS

FDA

  • Indicated for the treatment of human smallpox disease in adults and pediatric patients weighing at least 13 kg.
    • Limitation of use:
      • Effectiveness of tecovirimat treatment of smallpox disease has not been determined in humans because adequate and well-controlled field trials have not been feasible, and inducing smallpox disease in humans to study the drug’s efficacy is not ethical.
      • Efficacy may be reduced in immunocompromised patients based on animal models.

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