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- Indicated for the treatment of human smallpox disease in adults and pediatric patients weighing at least 13 kg.
- Limitation of use:
- Effectiveness of tecovirimat treatment of smallpox disease has not been determined in humans because adequate and well-controlled field trials have not been feasible, and inducing smallpox disease in humans to study the drug’s efficacy is not ethical.
- Efficacy may be reduced in immunocompromised patients based on animal models.
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