Voriconazole

Edina Avdic, Pharm.D.
Pediatric Dosing Author: Bethany Sharpless Chalk, Pharm.D., BCPPS

INDICATIONS

FDA

Voriconazole is FDA approved for the following indications in adults and pediatrics ≥ 2 years of age:
- Invasive aspergillosis
- Serious infections caused by Scedosporium apiospermum (Pseudallescheria boydii) and Fusarium spp. (including F. solani) in patients intolerant of, or refractory to, other therapies.
- Esophageal candidiasis
- Candidemia in non-neutropenic patients and other deep tissue Candida infections

NON-FDA APPROVED USES

Prophylaxis of invasive aspergillosis and disseminated candidiasis in severely immunocompromised hosts
Based on in-vitro data and limited clinical experience, voriconazole may be effective for infections due to certain dematiaceous fungi (C. immitis)

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