Sulfisoxazole

Kathryn Dzintars, Pharm.D., BCPS, Paul A. Pham, Pharm.D.
Sulfisoxazole is a topic covered in the Johns Hopkins ABX Guide.

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INDICATIONS

FDA

  • Urinary tract infection (pyelonephritis and cystitis)
  • Nocardia
  • Plasmodium falciparum, resistant to chloroquine.
  • Toxoplasmosis in combination with pyrimethamine (sulfadiazine preferred)
  • Otitis media (pediatric) in combination with PCN also trachoma including inclusion conjunctivitis, chancroid, meningococcal meningitis prophylaxis when sulfonamide-sensitive group A strains are known to prevail and meningitis caused by H. influenzae in combination with streptomycin (pediatric suspension)

NON-FDA APPROVED USES

  • Urinary tract infections in pregnancy

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INDICATIONS

FDA

  • Urinary tract infection (pyelonephritis and cystitis)
  • Nocardia
  • Plasmodium falciparum, resistant to chloroquine.
  • Toxoplasmosis in combination with pyrimethamine (sulfadiazine preferred)
  • Otitis media (pediatric) in combination with PCN also trachoma including inclusion conjunctivitis, chancroid, meningococcal meningitis prophylaxis when sulfonamide-sensitive group A strains are known to prevail and meningitis caused by H. influenzae in combination with streptomycin (pediatric suspension)

NON-FDA APPROVED USES

  • Urinary tract infections in pregnancy

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