Staphylococcal Toxic Shock Syndrome

Joel N. Blankson, M.D., Ph.D.

Staphylococcal Toxic Shock Syndrome is a topic covered in the Johns Hopkins ABX Guide.

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PATHOGENS

Staphylococcus aureus (MSSA or MRSA)
- Toxic shock toxin (TSS) occurs in ~1% of S. aureus strains.
- S. aureus produces the enterotoxins, TSST-1, SEB and SEC. These toxins are superantigens capable of activating up to 25% of T cells.

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PATHOGENS

Staphylococcus aureus (MSSA or MRSA)
- Toxic shock toxin (TSS) occurs in ~1% of S. aureus strains.
- S. aureus produces the enterotoxins, TSST-1, SEB and SEC. These toxins are superantigens capable of activating up to 25% of T cells.

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