Rifampin

Paul G. Auwaerter, M.D., Edina Avdic, Pharm.D.

INDICATIONS

INDICATIONS

INDICATIONS

FDA

FDA

FDA

  • All forms of tuberculosis.
  • Treatment of asymptomatic carriers of Neisseria meningitidis to eliminate meningococci from the nasopharynx.
  • Rifampin is used to reduce the development of drug-resistant bacteria and other antibacterial drugs--used only to treat or prevent infections proven or strongly suggested to be caused by bacteria.

NON-FDA APPROVED USES

NON-FDA APPROVED USES

NON-FDA APPROVED USES

  • Anthrax infections
  • Bartonella infections
  • Brucellosis
  • H. influenzae disease, chemoprophylaxis after close contact with a patient with invasive disease
  • Legionella infections
  • Meningitis caused by penicillin and ceftriaxone-resistantS. pneumoniae
  • N. meningitidis, chemoprophylaxis after close contact with a patient with invasive disease
  • Non-tuberculous mycobacterial infections (e.g., leprosy, MAC)
  • Prosthetic joint infections following debridement and retention of the prosthesis or 1-stage exchange.
  • Prosthetic valve endocarditis caused by staphylococci in combination with other agents (e.g., oxacillin/nafcillin, vancomycin) after blood cultures have cleared.
  • Q-fever and rickettsial infections
    • Used mainly in pregnant women
  • NOTE: Rifampin is usually used in combination with other agents due to the quick emergence of resistance if used as monotherapy.

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