Quinine

Edina Avdic, Pharm.D., Paul A. Pham, Pharm.D.
Pediatric Dosing Author: Alice Jenh Hsu, PharmD, BCPS, AQ-ID
Quinine is a topic covered in the Johns Hopkins ABX Guide.

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INDICATIONS

FDA

  • Oral quinine is indicated for the treatment of uncomplicated malaria (concurrently with tetracycline, doxycycline, clindamycin) in the treatment of chloroquine-resistant malaria caused by Plasmodium falciparum).
  • IV quinine is not available in the U.S.

NON-FDA APPROVED USES

  • Babesia species
  • Leg cramps. FDA advises against the use of quinine for leg cramps due to reports of severe hematologic adverse events.

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INDICATIONS

FDA

  • Oral quinine is indicated for the treatment of uncomplicated malaria (concurrently with tetracycline, doxycycline, clindamycin) in the treatment of chloroquine-resistant malaria caused by Plasmodium falciparum).
  • IV quinine is not available in the U.S.

NON-FDA APPROVED USES

  • Babesia species
  • Leg cramps. FDA advises against the use of quinine for leg cramps due to reports of severe hematologic adverse events.

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