Penicillin

Edina Avdic, Pharm.D., Paul A. Pham, Pharm.D.
Pediatric Dosing Author: Bethany Sharpless Chalk, Pharm.D., BCPPS

INDICATIONS

Endocarditis
Skin and soft tissue infection (erysipelas, erysipeloid)
Rat-bite fever
Vincent’s infection fusospirochetosis (Vincent’s gingivitis and pharyngitis)
Anthrax due to Bacillus anthracis, including inhalation anthrax (post-exposure): PCN procaine [note: CDC does not recommend as the first-line agent due to beta-lactamase production (see "biodefense-anthrax")]
Actinomycosis
Empyema
Pasteurella infections
Pneumonia
Upper respiratory tract infection: Group A strep pharyngitis, otitis media
Venereal infections (penicillin G benzathine suspension): syphilis and neurosyphilis
Rheumatic fever prophylaxis, chorea prophylaxis, glomerulonephritis prophylaxis, rheumatic heart disease

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