Osteomyelitis, Acute
Osteomyelitis, Acute is a topic covered in the Johns Hopkins ABX Guide.
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PATHOGENS
- Staphylococcus aureus (most common)
- Coagulase-negative staphylococci
- Streptococcus species
- Enterococcus
- Pseudomonas aeruginosa
- Escherichia coli
- Salmonella species
- Serratia species
- Kingella kingae
- Other Gram-negative enteric bacilli
- Much less common:
- Anaerobes
- Cutibacterium acnes
- Fungi
- Mycobacteria
- Brucella)
- Some typical settings:
- Hardware [S. aureus, coagulase-negative staphylococci (more with chronic), C. acnes (more commonly chronic presentation)]
- IV drug use (S. aureus, Pseudomonas, Serratia)
- Sickle cell (Salmonella)
- Diabetes (Group B strep)
- Nail through sneaker (Pseudomonas)
- Human bite (Eikenella)
- Animal bite (Pasteurella)
- Urinary tract infection or GU manipulation (E.coli, Proteus, other Gram-negative bacilli)
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