Osteomyelitis, Acute

Osteomyelitis, Acute is a topic covered in the Johns Hopkins ABX Guide.

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PATHOGENS

  • Staphylococcus aureus (most common)
  • Coagulase-negative staphylococci
  • Streptococcus species
  • Enterococcus
  • Pseudomonas aeruginosa
  • Escherichia coli
  • Salmonella species
  • Serratia species
  • Kingella kingae
  • Other Gram-negative enteric bacilli
  • Much less common:
    • Anaerobes
    • Cutibacterium acnes 
    • Fungi
    • Mycobacteria
    • Brucella)
  • Some typical settings:
    • Hardware [S. aureus, coagulase-negative staphylococci (more with chronic), C. acnes (more commonly chronic presentation)]
    • IV drug use (S. aureus, Pseudomonas, Serratia)
    • Sickle cell (Salmonella)
    • Diabetes (Group B strep)
    • Nail through sneaker (Pseudomonas)
    • Human bite (Eikenella)
    • Animal bite (Pasteurella)
    • Urinary tract infection or GU manipulation (E.coli, Proteus, other Gram-negative bacilli)

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PATHOGENS

  • Staphylococcus aureus (most common)
  • Coagulase-negative staphylococci
  • Streptococcus species
  • Enterococcus
  • Pseudomonas aeruginosa
  • Escherichia coli
  • Salmonella species
  • Serratia species
  • Kingella kingae
  • Other Gram-negative enteric bacilli
  • Much less common:
    • Anaerobes
    • Cutibacterium acnes 
    • Fungi
    • Mycobacteria
    • Brucella)
  • Some typical settings:
    • Hardware [S. aureus, coagulase-negative staphylococci (more with chronic), C. acnes (more commonly chronic presentation)]
    • IV drug use (S. aureus, Pseudomonas, Serratia)
    • Sickle cell (Salmonella)
    • Diabetes (Group B strep)
    • Nail through sneaker (Pseudomonas)
    • Human bite (Eikenella)
    • Animal bite (Pasteurella)
    • Urinary tract infection or GU manipulation (E.coli, Proteus, other Gram-negative bacilli)

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