Minocycline

Kathryn Dzintars, Pharm.D., BCPS, Paul A. Pham, Pharm.D.

INDICATIONS

Pneumonia due to Mycoplasma pneumoniae
Granuloma inguinale caused by Calymmatobacterium granulomatis
Lymphogranuloma venereum caused by Chlamydia species
Psittacosis caused by Chlamydia psittaci
Rocky Mountain spotted fever, typhus fever and the rickettsial typhus group, Q fever, rickettsialpox and other tick fevers caused by Rickettsiae
Relapsing fever due to Borrelia recurrentis
Chancroid caused by Haemophilus ducreyi
Cholera caused by Vibrio cholerae (resistance reported)
Nongonococcal urethritis (caused by Ureaplasma urealyticum or Chlamydia trachomatis)
Yaws caused by T. pertenue
Plague due to Yersinia pestis
Tularemia due to Francisella tularensis
Campylobacter fetus infections caused by Campylobacter fetus
Brucellosis due to Brucella species (in conjunction with streptomycin)
Bartonellosis due to Bartonella bacilliformis
Mild-moderate Acne vulgaris (age >12, minocycline ER only)
IV Minocycline is also indicated for the treatment of infections caused by the following Gram-negative bacteria when bacteriologic testing indicates appropriate susceptibility to the drug:
- E. coli
- Enterobacter aerogenes
- Shigella species
- Acinetobacter species
- Respiratory tract infections caused by H. influenzae and S. pneumoniae
- Skin and skin structure infections caused by S. aureus

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