Meropenem

Edina Avdic, Pharm.D.
Meropenem is a topic covered in the Johns Hopkins ABX Guide.

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Abdominal MassAbdominal Mass

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INDICATIONS

FDA

  • Intra-abdominal infections caused by viridans group streptococci, E. coli, K. pneumoniae, P. aeruginosa, B. fragilis, Bacteroides thetaiotaomicron, and Peptostreptococcus species.
  • Meningitis (children 3 months of age and older) caused by S. pneumoniae, H. influenzae, and N. meningitidis.
  • Complicated skin and soft tissue infections caused by S. aureus (MSSA only), S. pyogenes, Streptococcus agalactiae, viridans group streptococci,E. faecalis (not VRE), P. aeruginosa, E. coli, Proteus mirabilis, B. fragilis, and Peptostreptococcus species.

NON-FDA APPROVED USES

  • Hospital-acquired pneumonia
  • Necrotizing pancreatitis
  • Obstetric and gynecologic infections
  • Febrile neutropenia
  • Sepsis and bacteremia
  • Endocarditis caused by Gram-negative organisms (P. aeruginosa)
  • Infections caused by ESBL producing organisms
  • Multidrug resistant Gram-negative infections

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INDICATIONS

FDA

  • Intra-abdominal infections caused by viridans group streptococci, E. coli, K. pneumoniae, P. aeruginosa, B. fragilis, Bacteroides thetaiotaomicron, and Peptostreptococcus species.
  • Meningitis (children 3 months of age and older) caused by S. pneumoniae, H. influenzae, and N. meningitidis.
  • Complicated skin and soft tissue infections caused by S. aureus (MSSA only), S. pyogenes, Streptococcus agalactiae, viridans group streptococci,E. faecalis (not VRE), P. aeruginosa, E. coli, Proteus mirabilis, B. fragilis, and Peptostreptococcus species.

NON-FDA APPROVED USES

  • Hospital-acquired pneumonia
  • Necrotizing pancreatitis
  • Obstetric and gynecologic infections
  • Febrile neutropenia
  • Sepsis and bacteremia
  • Endocarditis caused by Gram-negative organisms (P. aeruginosa)
  • Infections caused by ESBL producing organisms
  • Multidrug resistant Gram-negative infections

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