Levofloxacin

Kathryn Dzintars, Pharm.D., BCPS, Paul G. Auwaerter, M.D.

INDICATIONS

Acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial sinusitis, uncomplicated urinary tract infections
- NOTE: Using levofloxacin for these indications should be avoided due to FDA warnings (black box warnings) regarding serious and potentially permanent side effects (tendinitis and tendon rupture, peripheral neuropathy, and CNS side effects). FDA safety warning regarding fluoroquinolone use
Pneumonia: community-acquired pneumonia and nosocomial pneumonia
Inhalational anthrax (post-exposure)
Uncomplicated and complicated skin and soft tissue infections (not Staphylococcus aureus)
Complicated urinary tract infections
Acute pyelonephritis
Bacterial conjunctivitis (Quixin 0.5% ophthalmic drops)
- Treatment of corneal ulcer (1.5% ophthalmic solution)
Chronic bacterial prostatitis

Treatment of M. tuberculosis, including MDR and XDR-TB (in combination with other agents)
Treatment of MAI and other non-TB mycobacterial infections (in combination with other agents)
Alternative therapy for treating S. pneumoniae and H. influenzae meningitis in patients with severe penicillin allergies
Bone and joint infections
Intra-abdominal infections in combination with metronidazole
H. pylori, in combination with other agents
Prophylaxis in neutropenic patients

There's more to see -- the rest of this topic is available only to subscribers.

All content is protected by copyright and may not be used for AI model training or other unauthorized purposes.