Fluconazole

Kathryn Dzintars Dzintars, Pharm.D., BCPS, Edina Avdic, Pharm.D.

INDICATIONS

INDICATIONS

INDICATIONS

FDA

FDA

FDA

  • Candidiasis prophylaxis (patients undergoing bone marrow transplant who receive cytotoxic chemotherapy and/or radiation therapy)
  • Oropharyngeal and esophageal candidiasis
  • Vulvovaginal candidiasis
  • Cryptococcal meningitis (treatment and suppression) in AIDS patients

NON-FDA APPROVED USES

NON-FDA APPROVED USES

NON-FDA APPROVED USES

  • Blastomycosis
  • Candida infections
    • Disseminated candidiasis and candidemia (including peritonitis)
    • Endophthalmitis
    • Osteoarticular infection and septic arthritis
    • UTIs
    • Endovascular - step-down therapy
    • CNS candidiasis - step-down therapy
    • Neonatal candidiasis
    • Prophylaxis: critically ill patients s/p GI surgery, candidal infection prevention
  • Cryptococcal infections: meningitis (non-HIV) and pulmonary infections (HIV, non-HIV)
  • Coccidioidomycosis
  • Histoplasmosis a
    • As an alternative therapy for mild to moderate diseases in patients intolerant to itraconazole.
  • Pityriasis versicolor
  • Tinea infections

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