Diloxanide furoate
Diloxanide furoate is a topic covered in the Johns Hopkins ABX Guide.
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INDICATIONS
FDA
FDA
- Drug not currently available for use in the U.S.
- Also known as in the literature as entamide furoate or entamide.
- CDC conducted a study with investigational use of the drug between 1977-1990.
NON-FDA APPROVED USES
NON-FDA APPROVED USES
- Amebiasis limited to the GI lumen, caused by Entamoeba histolytica.
- As combination therapy with other antiprotozoals such as nitroimidazoles for the treatment of invasive or extraintestinal amebiasis. Diloxanide furoate is not a tissue amoebicide and therefore in extraintestinal infections of E. histolytica, another agent (specifically a "tissue amoebicide" like Metronidazole) should be considered for use in combination with diloxanide furoate.
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INDICATIONS
FDA
FDA
- Drug not currently available for use in the U.S.
- Also known as in the literature as entamide furoate or entamide.
- CDC conducted a study with investigational use of the drug between 1977-1990.
NON-FDA APPROVED USES
NON-FDA APPROVED USES
- Amebiasis limited to the GI lumen, caused by Entamoeba histolytica.
- As combination therapy with other antiprotozoals such as nitroimidazoles for the treatment of invasive or extraintestinal amebiasis. Diloxanide furoate is not a tissue amoebicide and therefore in extraintestinal infections of E. histolytica, another agent (specifically a "tissue amoebicide" like Metronidazole) should be considered for use in combination with diloxanide furoate.
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