Colistimethate (colistin)

Paul A. Pham, Pharm.D., John G. Bartlett, M.D.
Colistimethate (colistin) is a topic covered in the Johns Hopkins ABX Guide.

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INDICATIONS

FDA

  • Enteritis (caused by E. coli)
  • External auditory canal infections (in combination with neomycin and hydrocortisone)
  • Mastoid infections (in combination with neomycin and hydrocortisone)
  • Shigella gastroenteritis
  • Acute or chronic infections due to sensitive strains of Pseudomonas aeruginosa
  • Cystic fibrosis
  • Disease due to Gram-negative bacteria: Enterobacter aerogenes, E. coli, Klebsiella pneumoniae

NON-FDA APPROVED USES

  • Infections caused by multi-drug resistant Acinetobacter baumannii, Klebsiella pneumoniae, and Pseudomonas aeruginosa.

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INDICATIONS

FDA

  • Enteritis (caused by E. coli)
  • External auditory canal infections (in combination with neomycin and hydrocortisone)
  • Mastoid infections (in combination with neomycin and hydrocortisone)
  • Shigella gastroenteritis
  • Acute or chronic infections due to sensitive strains of Pseudomonas aeruginosa
  • Cystic fibrosis
  • Disease due to Gram-negative bacteria: Enterobacter aerogenes, E. coli, Klebsiella pneumoniae

NON-FDA APPROVED USES

  • Infections caused by multi-drug resistant Acinetobacter baumannii, Klebsiella pneumoniae, and Pseudomonas aeruginosa.

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