Cefotetan

Paul G. Auwaerter, M.D., Edina Avdic, Pharm.D.
Pediatric Dosing Author: Alice Jenh Hsu, Pharm.D., BCPS

INDICATIONS

FDA

  • Urinary tract infections
  • Lower respiratory tract infections
  • Skin and skin structure infections
  • Gynecologic infections, including PID (note: no activity against C. trachomatis)
    • No longer recommended in 2022 STD Guideline.
  • Intra-abdominal infections (IDSA guidelines: cefotetan is no longer recommended for intra-abdominal infections as monotherapy due to high rates of B. fragilis resistance).
  • Bone and joint infections (author’s comment: generally used for mild infections)
  • Surgical prophylaxis (e.g., cesarean section, abdominal or vaginal hysterectomy, trans-urethral surgery, biliary tract surgery, and gastrointestinal surgery)

NON-FDA APPROVED USES

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