Caspofungin acetate

Paul A. Pham, Pharm.D., John G. Bartlett, M.D.

INDICATIONS

Treatment of invasive aspergillosis in patients who are refractory to or intolerant of other anti-fungal therapy.
- Candidemia and the following Candida infections: intra-abdominal abscesses, peritonitis and pleural space infections.
- Note: not well studied in endocarditis, osteomyelitis, and meningitis (low CNS penetration) due to Candida.
Esophageal candidiasis (authors’ opinion: would reserve caspofungin for azole-resistant cases).
Empiric treatment of presumed fungal infections in febrile neutropenic patients.

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